All eyes will be on exciting South African prospect Sokwakhana Zazini in the one-lap contest over the barriers.
Zazini, who set a world U18 best of 48.84 in Pretoria on 17 March, is the only athlete in the entry lists to have run faster than 51 seconds.
Also a formidable athlete in the flat 400m sprint, he will focus on the hurdles discipline with his eyes firmly focused on the clock.
Should he falter, his strongest challenges could come from Kenya’s Naadokila Moitalel Mpoke, who holds a personal best of 51.20, Ismail Manyani of Morocco (51.83) and Asian youth champion Halomoan Edwin Binsar of Indonesia (51.96).
Wesley Botton for the IAAF